What Is the Rationale for Giving Levodopa and Carbidopa as Combination

question 4

Multiple Choice

What is the rationale for giving levodopa and carbidopa as combination therapy for Parkinson's disease?

• A) Levodopa increases the therapeutic effect of carbidopa.
• B) Carbidopa inhibits the breakdown of levodopa, increasing distribution to the central nervous system.
• C) Both preparations are required to increase the availability of dopamine in the peripheries.
• D) Levodopa increases the half-life of carbidopa.

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Definitions:

Mycenae

An ancient city located in the Peloponnese of Greece, known for its significant archaeological sites from the Mycenaean civilization.

Spring Fresco

Refers to a fresco painting from the Bronze Age, found in Akrotiri on the island of Thera (modern Santorini), depicting a vibrant spring landscape.

Akrotiri

A Minoan Bronze Age settlement on the Greek island of Santorini, preserved under volcanic ash and known for its advanced architecture and frescoes.

Landscape

Depictions of natural scenery in art, emphasizing the aesthetics of nature and often featuring mountains, trees, rivers, or forests.