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Association Studies Compare Affected Individuals from Different Families with Unaffected

question 48

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Association studies compare affected individuals from different families with unaffected individuals, seeking to find genetic differences between those with and without a behavior disorder. Given the size and complexity of the human genome, do you think this approach can be used to systematically scan the genome for loci controlling behavior? How will you know when you have found one? How do you differentiate between polymorphisms and genuine differences?


Definitions:

Rate of Return

The profit or deficit from an investment during a certain timeframe, represented as a portion of the investment's starting price in percentage terms.

Simple Interest

A financial term referring to a method of calculating the interest charge on a loan or investment based on the original principal amount, the interest rate, and the time the loan or investment is made for.

Guaranteed Investment Certificate

A secure investment that guarantees to return the principal plus interest at a specified rate over a fixed period.

Annual Interest Rate

The percentage of principal that is paid as interest to the lender annually, not accounting for the compound interest within that year.

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