Which of the Following Mediators of Inflammation Causes Pain

question 4

Multiple Choice

Which of the following mediators of inflammation causes pain?

• A) Nitric oxide
• B) Complement C3a
• C) Bradykinin
• D) Leukotriene B₄
• E) Interleukin-1

---

Definitions:

Stratum Spinosum

Layer of many-sided cells in the epidermis with intercellular connections (desmosomes) that give the cells a spiny appearance.

Stratum Corneum

The outermost layer of the skin, composed of dead keratinocytes, that serves as the primary barrier against environmental elements.

Melanin

is a pigment produced by melanocytes in the skin, determining skin and hair color and providing protection against UV radiation.

Keratinocytes

The primary type of cell found in the epidermis, responsible for producing keratin.