A Mutation of the Gene Encoding the Hepatic Enzyme Bilirubin

question 16

Multiple Choice

A mutation of the gene encoding the hepatic enzyme bilirubin uridine diphosphate-glucuronyltransferase (UGT1A1) associated with congenital jaundice and a complete absence of UGT1A1 is called

• A) Crigler-Najjar syndrome type I
• B) Gilbert disease
• C) Dubin-Johnson disease
• D) Rotor syndrome
• E) Galactosemia

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Definitions:

Prediction Interval

An estimate of an interval in which future observations will fall, with a certain degree of confidence, based on a predictive model.

Linear Regression

A mathematical approach that models how a dependent variable changes based on one or several independent variables, by adapting a linear equation to the data collected.

Mean Value

The average of a set of numbers, calculated by dividing the sum of these numbers by the count of numbers in the set.

Model

A representation or abstraction of a process, system, or object that aims to explain, predict, or simulate real-world behavior, phenomena, or outcomes.