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A Physical Examination of a 5-Year-Old Girl Shows a Grape-Like

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A physical examination of a 5-year-old girl shows a grape-like polypoid mass protruding from the vagina. Histologic examination reveals that the mass has a myxoid stroma that contains small oval-shaped cells. Some of these cells have pink cytoplasm and resemble tennis rackets. These cells reacted positively upon immunohistochemical staining with the antibodies to desmin. Which of the following is the most likely diagnosis? A physical examination of a 5-year-old girl shows a grape-like polypoid mass protruding from the vagina. Histologic examination reveals that the mass has a myxoid stroma that contains small oval-shaped cells. Some of these cells have pink cytoplasm and resemble tennis rackets. These cells reacted positively upon immunohistochemical staining with the antibodies to desmin. Which of the following is the most likely diagnosis?   A)  Squamous cell carcinoma B)  Clear cell adenocarcinoma of the cervix C)  Leiomyosarcoma D)  Rhabdomyosarcoma E)  Malignant melanoma


Definitions:

Keratinized

Having become a structure that contains keratin, a protein found in skin, hair, nails, and horns.

Columnar

Shaped like a column.

Transitional

Relating to a process or period of changing from one state or condition to another.

Keratinized Squamous Epithelium

A type of epithelial tissue characterized by layers of cells that have undergone keratinization, providing a waterproof barrier.

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