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One problem that may cause MBO to fail is that
Kidney
An organ in vertebrates that filters waste products from the blood, regulates blood pressure, electrolyte balance, and red blood cell production.
Liver
Largest gland of the body, lying in the upper-right quadrant of the abdomen just inferior to the diaphragm; secretes bile and is of great importance in carbohydrate and protein metabolism and in detoxifying chemicals.
Hyperkalemia
Greater than normal concentration of potassium ions in the circulating blood.
Calcitonin
Hormone released from parafollicular cells that acts on tissues to cause a decrease in blood levels of calcium ions.
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