LFA-1 Is an Integrin That Promotes T Cell Activation by Which

question 16

Multiple Choice

LFA-1 is an integrin that promotes T cell activation by which one of the following mechanisms?

• A)Binds to the α3 domain of class I MHC molecules, mediating high avidity between T cells and antigen-presenting cells (APCs)
• B)Binds to B7-1 or B7-2 on the surface of APCs, mediating "signal 2"
• C)Binds to GlyCAM-1 on high endothelial venules of lymph nodes, mediating rolling of T cells on endothelium
• D)Binds to ICAM-1 on the surface of a variety of cells, mediating firm adhesion between T cells and APCs or endothelial cells
• E)Binds to VCAM-1 on the surface of cytokine-activated endothelial cells, mediating homing of T cells to peripheral sites of inflammation

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Definitions:

Attachment

An emotional bond that forms between individuals, typically between a child and caregiver, which influences the child's development and future relationships.

Intersexed

A term used to describe individuals born with physical sex characteristics that do not fit typical binary notions of male or female bodies.

Transsexual

A term describing a person whose gender identity differs from the sex they were assigned at birth, often undergoing medical procedures to transition.

Equal

Having the same value, quantity, or measure as another entity or condition.