Which of the Following Statements About Ig Isotype Switching Is

question 7

Multiple Choice

Which of the following statements about Ig isotype switching is NOT true?

• A)Interleukin-4 promotes switching to the IgE isotype by increasing germline transcription of the CϬ exon.
• B)Isotype switching involves recombination of a V(D)J complex with downstream C region genes and the deletion of intervening DNA including other C region genes.
• C)Activation-induced deaminase (AID) is required for switch recombination.
• D)The enzymes that mediate isotype switching recognize conserved heptamer and nonamer DNA sequences adjacent to the constant region exons.
• E)The same recombined V(D)J gene complex is used to encode the antigen-binding region of the antibodies produced by a B cell before and after isotype switching.

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Definitions:

Increase Assets

The act of growing the resources owned by an entity that have future economic value and can be measured and expressed in monetary units.

Business Entity Assumption

A principle in accounting that treats a business as separate from its owners or other businesses, allowing for independent financial accounting and reporting.

Accounting Equation

The accounting equation, Assets = Liabilities + Equity, is the fundamental formula in accounting, ensuring that a company's balance sheet is balanced.

Stockholders' Equity

The residual interest in the assets of a corporation that remains after deducting its liabilities, representing the owners' share.