The Figure Shows Routine Histologic and Immunofluorescence Images of a Kidney

question 3

Multiple Choice

The figure shows routine histologic and immunofluorescence images of a kidney biopsy specimen taken from a 53-year-old man with acute-onset renal failure and hemoptysis (coughing up blood) . The histologic section is notable for glomerular inflammation in a crescentic distribution. Staining, using fluorescently tagged anti-IgG antibody, shows linear deposits of IgG along the glomerular basement membrane. Urinalysis is positive for moderate proteinuria and red cell casts. A chest radiograph shows pulmonary infiltrates. Which of the following is the most likely diagnosis?

• A) Systemic lupus erythematosus
• B) Graves' disease
• C) Chronic allograft rejection
• D) Goodpasture's syndrome
• E) Poststreptococcal glomerulonephritis

---

Definitions:

Skewed

A description of a distribution that is not symmetrical, with a majority of data points lying on one side of the mean.

Width

The measurement of the extent of something from side to side, often used in reference to dimensions of objects.

Classes

Categories or groups into which data points or objects are organized based on defined criteria.

Largest Observation

The largest observation refers to the highest value or data point measured or collected within a dataset.