Which of the Following Is NOT an Example of a Checkpoint

question 10

Multiple Choice

Which of the following is NOT an example of a checkpoint in lymphocyte maturation that contributes to the selective maturation of cells with useful antigen receptors?

• A)B cell precursors that cannot express Ig g heavy chains die by apoptosis.
• B)T cell precursors that cannot express TCR b chains die by apoptosis.
• C)Immature B cells that bind to self antigen with high affinity die by apoptosis.
• D)Developing T cells that fail to express TCR a chains die by apoptosis.
• E)Developing T cells that recognize self major histocompatibility complex (MHC)molecules with high affinity die by apoptosis.

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