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From the Progressive Era forward, the benefit of at-large elections was argued to be that they:
Neuroendocrine Cells
Neurons that produce neurohormones.
Neurohormones
Hormones produced by neuroendocrine cells; transported down axons and released into interstitial fluid; common in invertebrates; in vertebrates, the hypothalamus produces neurohormones.
Interstitial Fluid
A fluid that fills the spaces between cells in tissues, providing nutrients and removing waste from cells.
Hypothalamus
A region of the brain responsible for hormone production and regulation of body temperature, hunger, moods, and sleep.
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