Some Drugs Like MDMA (Ecstasy, PKa 9

question 18

Multiple Choice

Some drugs like MDMA (Ecstasy, pKa 9.9) are so basic that they do not exist in any appreciable quantities in the neutral B form in the digestive tract. Yet, they are still absorbed. What factors allow for this?

• A) Very large surface area of the GI tract
• B) Rapid removal of any B molecules that do exist and transit the lipid bilayer
• C) Movement of the liquid phases on both sides of the lipid bilayer
• D) All of the above
• E) None of the above

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Definitions:

P-value

The probability of obtaining test results at least as extreme as the results observed, assuming that the null hypothesis is true.

Pearson Correlation

A measure of the linear correlation between two variables, giving a value between -1 and 1 where 1 implies a positive linear correlation, -1 a negative linear correlation, and 0 no linear correlation.

Null Hypothesis

A hypothesis that there is no significant difference or effect, serving as the default assumption to test against in statistical analysis.

Maximum Temperature

The highest recorded temperature in a specified period or area.