What Controls the Intrinsic Solubility (S₀) of a Drug with an Ionizable

question 29

Multiple Choice

What controls the intrinsic solubility (S₀) of a drug with an ionizable center?

• A) the polarity of B or HA form
• B) Ksp of the drug salt
• C) pH and pKa
• D) K_D
• E) none of the above

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Definitions:

Single Insertion

When a muscle or tendon attaches to bone at one point or site.

Brachialgia

Pain in the arm, often deriving from nerve irritation or damage.

Pain

A disagreeable feeling and emotional response linked to real or possible harm to the body's tissues.

Tenodynia

Pain in a tendon, often due to strain or overuse.