Position-Specific Weight Matrix Tables Show Relatively Few Substitutions for Cysteine

question 25

Multiple Choice

Position-specific weight matrix tables show relatively few substitutions for cysteine and tryptophan compared with other proteins. Which of the following are possible explanations for this? Please select all that apply.

• A) Cysteine and tryptophan are more likely to have essential roles in the mature protein than other amino acids
• B) Cysteine and tryptophan are larger than other amino acids.
• C) Cysteine and tryptophan have unusual structures
• D) The codons for cysteine and tryptophan are similar to a stop codon

---

Definitions:

Least-squares Regression

A statistical method used to determine the line of best fit by minimizing the sum of the squares of the differences between observed and predicted values.

Fixed Component

A portion of overall costs that does not change in the short term, regardless of the level of output or activity.

Maintenance Cost

Expenses associated with the upkeep and repair of equipment or facilities to ensure their proper functioning and efficiency.

Variable Component

A part or element of production costs or expenses that changes in proportion to the level of output or activity.