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Tumor-suppressor Genes
Genes that protect a cell from one step on the path to cancer; when these genes are mutated or inactivated, the risk of cancer development increases.
Defective Alleles
Variants of genes that do not function correctly, often leading to disorders or reduced fitness in organisms.
Somatic Mutations
Genetic alterations acquired by a cell that can be passed to the progeny of the mutated cell but not to an individual's offspring.
HbS Allele
A variant of the hemoglobin gene responsible for sickle-cell disease, offering protection against malaria where prevalent.
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