Kawakubo's Group Created a Glycoprotein with a Terminal NAG (I

question 20

Multiple Choice

Kawakubo's group created a glycoprotein with a terminal NAG (i.e.,a protein with NAG attached to its end) .Their hypothesis is that the terminal NAG-and not the protein component-is responsible for the damage to the cell wall in H.pylori.What would be the most appropriate control for testing this hypothesis?

• A)Grow H.pylori in a test tube (in vitro)with no glycoprotein.
• B)Destroy the H.pylori by exposing them to a hypotonic solution.Then add the glycoprotein and observe.
• C)Expose other species of bacteria to the glycoprotein.
• D)Grow H.pylori in a test tube with glycoprotein that has its terminal NAG removed.

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