Hereditary Nonpolyposis Colorectal Cancer (HNPCC)is an Inherited Disorder

question 10

Multiple Choice

Hereditary nonpolyposis colorectal cancer (HNPCC) is an inherited disorder.The genetic defect identified is an error in the mismatch repair mechanism.Which of the following would be an expected result of this mutation?

• A)increased rate of errors by wild-type DNA polymerase
• B)increased rate of formation of pyrimidine dimers
• C)increased rate of repair of pyrimidine dimers
• D)decreased ability to repair certain DNA mutations

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