Polylysine Is a Random Coil When the PH Is Less

question 27

Multiple Choice

Polylysine is a random coil when the pH is less than 11,while it forms an a-helix if the pH is raised to greater than 12.What happens at pH 12 to account for this?

• A)The lysine residues are negatively charged,which electrostatically stabilizes the helix.
• B)The positive charges on the lysine residues stabilize the a-helix.
• C)The lysine residues are neutral,which eliminates electrostatic repulsion between the R groups.
• D)The high concentration of OH⁻ ions in solution reduces the electrostatic repulsion between the R groups.

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