How Does the "Hole in the T Cell Repertoire" Model

question 9

Multiple Choice

How does the "hole in the T cell repertoire" model explain why some individuals may fail to respond to an antigen?

• A) MHC class II molecules differ in their ability to bind and process antigen.
• B) The TCR is lacking appropriate accessory molecules to fully transduce signals.
• C) Some individuals lack a lymphocyte with a TCR that recognizes a specific antigen.
• D) Antigen is inappropriately presented on MHC class I molecules rather than class II molecules.

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Definitions:

Oxygen Transport

The process of delivering oxygen from the lungs to the tissues via the blood.

Leukocytes

White blood cells that are part of the immune system, involved in protecting the body against both infectious disease and foreign invaders.

Neutrophil

A type of white blood cell important in the immune system's response to infection.

Eosinophil

A type of white blood cell involved in allergic reactions and defense against parasites.