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Use the Figure Below and Describe the General Mechanism of How

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Use the figure below and describe the general mechanism of how supercoiling can be introduced in a double-stranded, circular DNA molecule. In this example, this DNA is about 300 bp.
Use the figure below and describe the general mechanism of how supercoiling can be introduced in a double-stranded, circular DNA molecule. In this example, this DNA is about 300 bp.


Definitions:

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