The Average Mutation Rate for DNA Replication Is 1 Mutation

question 35

Multiple Choice

The average mutation rate for DNA replication is 1 mutation for every 10 billion (10,000,000,000) nucleotides of DNA replicated. Yet DNA polymerase makes a mistake during replication at an average of 1 in 100,000 nucleotides. What does this say about DNA replication?

• A) Most errors in DNA replication become mutations.
• B) The base-pairing rules (A pairs with T and G pairs with C) prevent any mutations.
• C) Cells are extraordinarily proficient at repairing errors made during DNA replication.
• D) Cells recognize that a small fraction of mutations are beneficial to organisms and do not repair those.

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Definitions:

Least-Squares Prediction

A method used in linear regression to estimate the value of a dependent variable based on the minimum sum of squared deviations from the predicted values.

Prediction Of Y

Estimating the value of the dependent variable in a regression analysis based on the independent variable(s).

Significance Level

The probability of rejecting the null hypothesis when it is actually true, used as a threshold in hypothesis testing.

Model Contribution

Refers to the impact or influence that a statistical model has in explaining the variability of the observed data.