In the Experiment Shown in the Figure Above,Tonegawa and His

question 11

Multiple Choice

In the experiment shown in the figure above,Tonegawa and his colleagues were able to express β-globin in an antibody-producing cell that normally does not express β-globin.They achieved this result by splicing an enhancer from an antibody-producing gene into the protein-coding portion of the β-globin gene.They then introduced this recombinant gene into cultured antibody-producing cells.Why was the choice of antibody-producing cells rather than,say,muscle or skin cells critical for the success of this experiment?

• A)Only the antibody-producing cells have the correct regulatory transcription factors to bind to the enhancer.
• B)Only the antibody-producing cells have the correct set of enhancers.
• C)Only the antibody-producing cells have the correct set of promoter-proximal elements.
• D)Only the antibody-producing cells have the correct set of enhancers,promoter-proximal elements,and promoters.
• E)Only the antibody-producing cells are capable of expressing recombinant genes.

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Definitions:

Antigen

A substance that can induce an immune response, often seen as foreign by the body's immune system.

Species Resistance

The natural ability of a species to resist or fend off infections and diseases due to inherent genetic or physiological factors.

Naturally Acquired

Immunity or resistance developed through natural exposure to pathogens rather than through vaccination.

Artificially Acquired

Refers to immunity gained through vaccines or by getting an injection of antibodies.