In the Experiment Shown in the Figure Above,Tonegawa and His

question 11

Multiple Choice

In the experiment shown in the figure above,Tonegawa and his colleagues were able to express β-globin in an antibody-producing cell that normally does not express β-globin.They achieved this result by splicing an enhancer from an antibody-producing gene into the protein-coding portion of the β-globin gene.They then introduced this recombinant gene into cultured antibody-producing cells.Why was the choice of antibody-producing cells rather than,say,muscle or skin cells critical for the success of this experiment?

• A)Only the antibody-producing cells have the correct regulatory transcription factors to bind to the enhancer.
• B)Only the antibody-producing cells have the correct set of enhancers.
• C)Only the antibody-producing cells have the correct set of promoter-proximal elements.
• D)Only the antibody-producing cells have the correct set of enhancers,promoter-proximal elements,and promoters.
• E)Only the antibody-producing cells are capable of expressing recombinant genes.