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The authors state:
"In this study,we report that,in the absence of neuronal activity,MeCP2 binds specifically to BDNF promoter III and functions as a negative regulator of BDNF expression.In response to neuronal activity-dependent calcium influx into neurons,MeCP2 becomes phosphorylated and is released from the BDNF promoter,thereby permitting BDNF promoter III-dependent transcription." Reading this statement in isolation,it would be easy to have the impression that MeCP2 works as a negatively acting transcription factor.However,based on the summary of the paper provided above,MeCP2 acts as a _____.
Domestic
Referring to aspects of the home or household, or pertaining to activities done within a country.
Vertical Gene Transfer
The transfer of genetic material from parent to offspring. Compare with horizontal gene transfer.
Genes
Sequences of DNA that contain the instructions for the development, functioning, growth, and reproduction of all known living organisms and viruses.
Species
The basic unit of biological classification, defined as a group of living organisms consisting of similar individuals capable of exchanging genes or interbreeding.
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