What Makes a Frameshift Mutational Event More Serious Than a Point

question 13

Multiple Choice

What makes a frameshift mutational event more serious than a point mutational event?

• A)Frameshift mutations occur primarily in germline cells, and point mutations occur only in somatic cells.
• B)Frameshift mutations result in the deletion or addition of whole chromosomes (aneuploidy), and point mutations are undetectable at the chromosome level.
• C)The rate of frameshift mutations increases with aging because DNA repair mechanisms decline, whereas the rate of point mutations is unchanged with age.
• D)When the mutations occur in expressed genes, frameshift mutations always result in disruption of the gene function, whereas a point mutation can be silent.

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