What Is the Best Explanation for a Person Whose Karyotype

question 5

Multiple Choice

What is the best explanation for a person whose karyotype from blood cells shows nearly all cells to have trisomy 21 to have 10 clinical manifestations of Downsyndromeand an above-average intelligence?

• A)The trisomy was a result of nondisjunction of paternal gametes instead of maternal gametes.
• B)The person has pseudo-Down syndrome, in which environmental conditions caused the person to have development that mimics only the physical manifestations.
• C)The person has genomic imprinting, in which the paternal number 21 chromosome is not expressed, and both maternally derived number 21 chromosomes are expressed.
• D)The person has mosaicism of trisomy 21, with blood cells having a high proportion and neurons having a low proportion of cells, with three number 21 chromosomes.

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Definitions:

Condensed Structural Formula

A method of representing the molecules of a compound using lines for bonds and showing the arrangement of connected atoms, but omitting bonding hydrogen atoms.

Methylbutane

An organic compound also known as isopentane, a type of alkane with the formula C5H12.

Dimethylpropane

A branched alkane with the formula C5H12, also known as isopentane, a component of some fuels.

Methyloctane

A type of hydrocarbon compound characterized by its chemical structure that includes an octane backbone with a methyl group attached.