Which of the Following Mechanisms in Fragile X Syndrome (FXS)

question 12

Multiple Choice

Which of the following mechanisms in fragile X syndrome (FXS) leads to expression of the disorder?

• A)Trinucleotide repeat sequences interspersed with the exons of the FMR1 gene, resulting in the production of an abnormal protein
• B)Trinucleotide repeat sequences causing methylation of the FMR1 gene, thus silencing its expression
• C)Increased production of microRNA molecules that interfere with the transcription of the FMR1 gene
• D)Increased production of microRNA molecules that interfere with the translation of the FMR1 gene

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