If a Man with Gaucher Type 1 Has Children with a Woman

question 22

Multiple Choice

If a man with Gaucher type 1 has children with a woman who is a carrier for the disorder, what is the expected risk pattern?

• A)All sons will be unaffected; all daughters will be carriers.
• B)All sons will be carriers; all daughters will be affected.
• C)All children will have one mutated allele and will at least be carriers; each child of either gender has a 50% risk of having the disease.
• D)Each child of either gender has a 50% risk of being a carrier, a 25% risk of having the disease, and a 25% risk of neither being a carrier nor having the disease.

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Definitions:

Animals

Multicellular, eukaryotic organisms of the kingdom Animalia that are capable of locomotion, responsive to their environment, and feed by consuming other organisms.

Androgen

A type of hormone that plays a role in male traits and reproductive activity; testosterone is the most well-known androgen.

Testosterone

A steroid hormone that plays a key role in the development of male reproductive tissues, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.

Estrogen

A group of steroid hormones that play an essential role in the development and regulation of the female reproductive system and secondary sex characteristics.