Why Are Single-Nucleotide Polymorphisms (SNPs), Which Have Been Associated with Schizophrenia

question 8

Multiple Choice

Why are single-nucleotide polymorphisms (SNPs) , which have been associated with schizophrenia and bipolar disorder, currently not used to diagnose either of these disorders?

• A)The changes in gene activity caused by the SNPs is not sufficient to cause disease expression.
• B)SNPs are associated with nicotine dependence but not with schizophrenia or bipolar disorder.
• C)The SNPs are too small to result in either a frameshift mutation or a point mutation.
• D)These SNP-induced gene changes cannot be altered by pharmacologic therapy.

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