What Is the Role of the Magnesium Ion in Kinases

question 8

Multiple Choice

What is the role of the magnesium ion in kinases that require the magnesium-ATP complex to donate phosphoryl groups?

• A)Maintain the configuration of the holoenzyme.
• B)Shield the charged phosphate groups of ATP.
• C)Produce an electrophilic attack on the substrate.
• D)Promote ionization of bound water.
• E)Produce ionization of the substrate to be phosphorylated.

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Definitions:

Isotope

Variants of a particular chemical element which differ in neutron number, and consequently in nucleon number, but have the same number of protons in their nuclei.

Protons

Positively charged subatomic particles found in the nucleus of an atom, defining the element's atomic number.

Osmium

A dense, hard, bluish-white transition metal in the platinum group that is the most dense naturally occurring element.

Isotope

A variant of a particular chemical element which differs in neutron number, though it shares the same number of protons.