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A Number of Systems for Pumping Across Membranes Are Powered

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A number of systems for pumping across membranes are powered by ATP. Such ATP-powered pumps are often called ATPases although they don't often hydrolyze ATP unless they are simultaneously transporting ions. Small increases in calcium ions in the cytosol trigger a number of different intracellular reactions, so the cells must keep the calcium concentration quite low. Muscle cells also transport calcium from the cytosol into the membranous system called the sarcoplasmic reticulum (SR) . If a muscle cell cytosol has a free calcium ion concentration of 10-⁷ in a resting cell, while the concentration in the SR can be 10-², then how is the ATPase acting?


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