A Phenotypically Normal Prospective Couple Seeks Genetic Counseling Because the Man

question 51

Multiple Choice

A phenotypically normal prospective couple seeks genetic counseling because the man knows that he has a translocation of a portion of his chromosome 4 that has been exchanged with a portion of his chromosome 12. Although he is normal because his translocation is balanced, he and his wife want to know the probability that his sperm will be abnormal. What is your prognosis regarding his sperm?

• A)1/4 will be normal, 1/4 with the translocation, 1/2 with duplications and deletions.
• B)All will carry the same translocation as the father.
• C)None will carry the translocation since abnormal sperm will die.
• D)His sperm will be sterile and the couple might consider adoption.
• E)1/2 will be normal and the rest with the father's translocation.

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Definitions:

Uncertainty

A situation where the outcomes or variables of a situation are unpredictable, often leading to risk in economic and financial decisions.

International Incident

An event that might cause tension or conflict between nations, often involving diplomatic, military, or political issues.

Present Value

The current worth of a future sum of money or stream of cash flows given a specified rate of return.

Expected Income Stream

The anticipated series of payments or revenues over a specified period.