Use the Following Information to Answer the Following Questions

question 5

Multiple Choice

Use the following information to answer the following questions.
CML (chronic myelogenous leukemia) results from a translocation between human chromosomes 9 and 22. The resulting chromosome 22 is significantly shorter than the usual, and it is known as a Philadelphia (Ph') chromosome. The junction at the site of the translocation causes over-expression of a thymine kinase receptor. A new drug (Gleevec or imatinib) has been found to inhibit the disease if the patient is treated early.
-Which of the following would be a reasonably efficient technique for confirming the diagnosis of CML?

• A)searching for the number of telomeric sequences on chromosome 22
• B)looking for a Ph' chromosome in a peripheral blood smear
• C)enzyme assay for thymine kinase activity
• D)FISH study to determine the chromosomal location of all chromosome 22 q fragments
• E)identification of the disease phenotype in review of the patient's records

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Definitions:

Competitive Market

A market structure characterized by a large number of buyers and sellers, free entry and exit, and products that are close substitutes, leading to price determination by supply and demand.

Coconuts

Tropical fruits with a hard outer shell and milky interior, known for their versatility in food products and industrial uses.

Fish

Aquatic animals that are typically cold-blooded, covered with scales, and equipped with fins, used as a significant food source for humans.

Comparative Advantage

An economic principle that refers to the ability of an entity to produce goods or services at a lower opportunity cost than others, leading to more efficient trade.