Unequal Crossing Over During Prophase I Can Result in One

question 34

Multiple Choice

Unequal crossing over during Prophase I can result in one sister chromosome with a deletion and another with a duplication. A mutated form of hemoglobin, known as hemoglobin Lepore, is known in the human population. Hemoglobin Lepore has a deleted set of amino acids. If it was caused by unequal crossing over, what would be an expected consequence?

• A)If it is still maintained in the human population, hemoglobin Lepore must be selected for in evolution.
• B)There should also be persons born with, if not living long lives with, an anti-Lepore mutation or duplication.
• C)Each of the genes in the hemoglobin gene family must show the same deletion.
• D)The deleted gene must have undergone exon shuffling
• E)The deleted region must be located in a different area of the individual's genome.

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Definitions:

Life Cycle

The series of stages through which a living organism passes from the beginning of its life until its death.

Maternal Effect

Phenomena where the genotype of the mother directly influences the phenotype of her offspring, due to substances present in the egg.

Polarity

A property of molecules having distinct and opposite ends, leading to asymmetrical distribution of charges.

Embryonic

Pertaining to the embryo; the initial stages of development in multicellular organisms after fertilization.