In Order to Determine the Probable Function of a Particular

question 36

Multiple Choice

In order to determine the probable function of a particular sequence of DNA in humans, what might be the most reasonable approach?

• A) Prepare a knockout mouse without a copy of this sequence and examine the mouse phenotype.
• B) Genetically engineer a mouse with a copy of this sequence and examine its phenotype.
• C) Look for a reasonably identical sequence in another species, prepare a knockout of this sequence in that species, and look for the consequences.
• D) Prepare a genetically engineered bacterial culture with the sequence inserted and assess which new protein is synthesized.
• E) Mate two individuals heterozygous for the normal and mutated sequences.

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Definitions:

Crisis Decision

A decision required when an unexpected problem arises that can lead to disaster if not resolved quickly and appropriately.

Nonprogrammed Decision

Decisions made in response to unique, non-routine, and unpredictable situations, requiring custom solutions and creative problem-solving.

Unstructured Problems

Issues or challenges that lack a clear procedure or path for resolution, often requiring creative solutions.

Nonprogrammed Decisions

Decisions made in response to situations that are unique, poorly defined, and largely unstructured, often requiring creative solutions.