Within a Few Weeks of Treatment with the Drug 3TC

question 45

Multiple Choice

Within a few weeks of treatment with the drug 3TC, a patient's HIV population consists entirely of 3TC-resistant viruses. How can this result best be explained?

• A)HIV can change its surface proteins and resist vaccines.
• B)The patient must have become reinfected with 3TC-resistant viruses.
• C)HIV began making drug-resistant versions of reverse transcriptase in response to the drug.
• D)A few drug-resistant viruses were present at the start of treatment, and natural selection increased their frequency.
• E)The drug caused the HIV RNA to change.

---

Definitions:

Promotional Allowance

A discount or financial incentive provided to retailers or wholesalers to encourage the promotion and sale of a product.

Gross Margin

The difference between revenue and cost of goods sold (COGS), expressed as a percentage of revenue, indicating the financial health and efficiency of a company's production process.

Price Special Promotion

Refers to temporary measures undertaken by a business to reduce prices or offer discounts to boost sales of products or services.

Geographic Adjustments

Modifications made to prices, wages, or data taking into account the geographical differences such as cost of living or market conditions.