A Bone Marrow Transplant May Not Be Appropriate from a Given

question 77

Multiple Choice

A bone marrow transplant may not be appropriate from a given donor (Jane) to a given recipient (Jane's cousin Bob) , even though Jane has previously given blood for one of Bob's needed transfusions. Which of the following might account for this?

• A)Jane's blood type is a match to Bob's but her MHC proteins are not.
• B)A blood type match is less stringent than a match required for transplant because blood is more tolerant of change.
• C)For each gene, there is only one blood allele but many tissue alleles.
• D)Jane's class II genes are not expressed in bone marrow.
• E)Bob's immune response has been made inadequate before he receives the transplant.