Why Would Levodopa Be Administered Instead of Oral DA to Help

question 21

Multiple Choice

Why would Levodopa be administered instead of oral DA to help treat Parkinson's disease?

• A)Bioavailability of oral DA is limited because it does not cross the blood-brain barrier.
• B)DA would be rapidly metabolized by catechol-O-methyltransferase (COMT)in the gastrointestinal (GI)tract,reducing bioavailability.
• C)Levodopa causes less adverse effects than oral DA would.
• D)Levodopa and oral DA are typically prescribed equally to treat Parkinson's disease.

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