In Graves Disease (Hyperthyroidism), Autoantibodies Bind to and Activate Receptors

question 20

Multiple Choice

In Graves disease (hyperthyroidism) , autoantibodies bind to and activate receptors for thyroid-stimulating hormone (TSH) so that excessive T₄ (thyroxine) is secreted, causing clinical manifestations of an increased metabolism.This mechanism is an example of which type II hypersensitivity reaction?

• A)Modulation
• B)ADCC
• C)Neutrophil-mediated damage
• D)Complement-mediated lysis

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Definitions:

Hydrogenation

The chemical process of adding hydrogen to an organic compound, usually to reduce or saturate organic molecules.

Stable Alkene

An alkene (hydrocarbon with carbon-carbon double bonds) that exhibits low reactivity due to its substituents or molecular structure.

Stable Alkene

An alkene that exhibits resilience against chemical reactions due to its specific structure, substitution pattern, or steric hindrance.

Dehydrogenated

Describes a chemical reaction in which hydrogen is removed from a molecule, often leading to the formation of double bonds or the introduction of oxygen atoms.