The Pathophysiologic Process Responsible for the Hemolytic-Uremic Syndrome Is That

question 29

Multiple Choice

The pathophysiologic process responsible for the hemolytic-uremic syndrome is that:

• A)an autoimmune disorder in which immunoglobulin A (IgA) coats erythrocytes that are destroyed by the spleen and remnants are excreted through the kidneys.
• B)verotoxin from E. coli is absorbed from the intestines and damages erythrocytes and endothelial cells.
• C)endotoxins from E. coli block the erythropoietin produced by the kidneys, which reduces the number of erythrocytes produced by the bone marrow.
• D)failure of the nephron to filter urea increases the blood urea nitrogen, which binds to erythrocytes that are subsequently destroyed by the spleen.

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