Normal Hemoglobin Is a Tetramer, Consisting of Two Molecules of β

question 70

Multiple Choice

Normal hemoglobin is a tetramer, consisting of two molecules of β hemoglobin and two molecules of α hemoglobin. In sickle-cell disease, as a result of a single amino acid change, the mutant hemoglobin tetramers associate with each other and assemble into large fibres. Based on this information alone, we can conclude that sickle-cell hemoglobin exhibits

• A)altered primary structure.
• B)altered secondary structure.
• C)altered tertiary structure.
• D)altered quaternary structure.
• E)altered primary structure and altered quaternary structure; the secondary and tertiary structures may or may not be altered.

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Definitions:

N3 Sleep

The deepest stage of Non-REM (NREM) sleep, characterized by slow brain waves and considered essential for restorative sleep and memory consolidation.

Sleep Cycle

The progression through various stages of non-REM and REM sleep that occurs repeatedly during a typical night's rest.

Hypertension

A medical condition in which the blood pressure in the arteries is persistently elevated, which can lead to serious health issues like heart disease.

Heart Disease

A range of conditions that affect the heart, including blood vessel diseases, heart rhythm problems, and heart defects.