One Hereditary Disease in Humans, Called Xeroderma Pigmentosum (XP), Makes

question 40

Multiple Choice

One hereditary disease in humans, called xeroderma pigmentosum (XP) , makes homozygous individuals exceptionally susceptible to UV-induced mutation damage in the cells of exposed tissue, especially skin. Without extraordinary avoidance of sunlight exposure, patients soon succumb to numerous skin cancers.
-Which of the following best describes this phenomenon?

• A) inherited cancer taking a few years to be expressed
• B) embryonic or fetal cancer
• C) inherited predisposition to mutation
• D) inherited inability to repair UV-induced mutation
• E) susceptibility to chemical carcinogens

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