The Biggest Problem with the Shotgun Technique Is Its Tendency

question 24

Multiple Choice

The biggest problem with the shotgun technique is its tendency to underestimate the size of the genome. Which of the following might best account for this?

• A)skipping some of the clones to be sequenced
• B)missing some of the overlapping regions of the clones
• C)counting some of the overlapping regions of the clones twice
• D)having some of the clones die during the experiment and therefore not be represented
• E)short repetitive sequences hinder reassembly

---

Definitions:

Average Rate

A calculated value that represents the central or typical value of a set of numbers, dividing the total by the number of values.

Movement

The action or process of changing position or place.

Geologists

Scientists who study the Earth, its materials, and the processes affecting it over time.

Natural Hazards

Phenomena that occur in nature like earthquakes, floods, and hurricanes, which can pose risks to human health, safety, and property.