How Does OnabotulinumtoxinA (BOTOX)therapeutically Produce Paresis in Overactive Muscles

question 5

Multiple Choice

How does onabotulinumtoxinA (BOTOX) therapeutically produce paresis in overactive muscles?

• A)Acts as an antagonist by binding to the ACh receptor on the postsynaptic membrane.
• B)Rapidly degrades ACh in the synaptic cleft.
• C)Facilitates the reuptake and sequestration of ACh into the presynaptic cell.
• D)Disrupts the protein structure of the muscle cell receptor,thus preventing ACh from binding.
• E)Inhibits the release of ACh from the presynaptic terminal at the neuromuscular junction.

---

Definitions:

Carrying Amounts

The value at which an asset is recognized on the balance sheet, after deducting accumulated depreciation or amortization.

Goodwill

An intangible asset that arises when a buyer acquires an existing business at a price higher than the fair market value of its net identifiable assets.

Fair Market Value

is an estimate of the market value of a property, based on what a knowledgeable, willing, and unpressured buyer would likely pay to a knowledgeable, willing, and unpressured seller in the market.

Identifiable Assets

Assets that can be separately identified and valued in a business combination, distinguishable from goodwill.