Two Different Subtypes of Matrix Metalloproteinase, Enzymes MMP-2 and MMP-9

question 8

Multiple Choice

Two different subtypes of matrix metalloproteinase, enzymes MMP-2 and MMP-9, are released from a squamous cell carcinoma.The enzymes behave according to Michaelis-Menten kinetics by the measured parameters in the table, in the same substrate:
Оn the basis of these data, which of the following is a true statement?

• A)MMP-2 makes more product than MMP-9 at the same enzyme concentrations.
• B)MMP-2 is more stable to proteolytic degradation than MMP-9.
• C)MMP-2 is denatured in the extracellular environment faster than MMP-9.
• D)MMP-2 is more active at its maximal velocity than MMP-9.
• E)MMP-2 reaches half-maximal velocity at a higher substrate concentration than does MMP-9.

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