A Type of Somatic Mutation That Inhibits Apoptosis and Thereby

question 4

Multiple Choice

A type of somatic mutation that inhibits apoptosis and thereby permits the survival of deviant cells is:

• A)Loss of the gene for Akt (protein kinase B).
• B)Amplification of the retinoblastoma gene.
• C)Loss of the gene for PTEN, the lipid phosphatase that destroys phosphatidylinositol-3,4,5-trisphosphate.
• D)Loss of the gene for the p53-binding protein Mdm2.
• E)Amplification of the gene for E2F.

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Definitions:

Golgi Bodies

Cell organelles that modify, package, and sort proteins and lipids for secretion or for use within the cell.

Schwann Cells

Glial cells in the peripheral nervous system that wrap around axons, forming the myelin sheath and aiding in the rapid transmission of neural signals.

Peripheral Nervous System

The Peripheral Nervous System consists of the nerves and ganglia outside the brain and spinal cord, responsible for transmitting signals to and from the central nervous system.

Central Nervous System

The part of the nervous system consisting of the brain and spinal cord, which integrates information and coordinates bodily functions and activities.