Hemoglobin C Disease Has Altered Solubility Properties Similar to Hemoglobin

question 14

Multiple Choice

Hemoglobin C disease has altered solubility properties similar to hemoglobin S disease. What accounts for this altered solubility?

• A) Heme iron is in the ferric form rather than ferrous form.
• B) The hemoglobin remains in the tense structure.
• C) A nonpolar amino acid is substituted for a polar amino acid.
• D) A polar amino acid is substituted near the pocket where heme binds.