Why Are Bone Changes and Deformities Common Findings in β-Thalassemias

question 15

Multiple Choice

Why are bone changes and deformities common findings in β-thalassemias?

• A) The globin chain synthesis is increased.
• B) The impaired globin chain synthesis causes erythroid hypoplasia.
• C) The impaired globin chain synthesis causes increased erythropoiesis resulting in bone marrow expansion.
• D) The impaired globin chain synthesis causes impaired oxygen delivery to the bone tissue, which causes bone deformities.

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