Alagille Syndrome Involves a Failure of Proper Segmentation of the Paraxial

question 7

Multiple Choice

Alagille syndrome involves a failure of proper segmentation of the paraxial mesoderm,ultimately resulting in defects of the vertebral column.Which signaling pathway is mutated in patients with Alagille?

• A) Notch-Delta
• B) TGF-beta
• C) Tyrosine Kinase
• D) Ephrin-EPH
• E) Integrin

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