Development of the Sensory Regions of the Inner Ear Involves

question 8

Multiple Choice

Development of the sensory regions of the inner ear involves the formation of hair cells and supporting cells by the process of lateral inhibition controlled by Notch signaling.How would overexpression of the transcription factors Hes1 and 5,which are modulated by Notch signaling,be expected to affect the number of hair cells or supporting cells?

• A) The overall number of supporting cells would increase.
• B) The overall number of supporting cells would decrease.
• C) The overall number of hair cells would increase.
• D) The overall number of hair cells would decrease.
• E) No change would occur in the number of hair cells or supporting cells.

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